PRIMARY STUDY

Inhibitory Effects of β-Caryophyllene on Helicobacter pylori Infection: A Randomized Double-blind, Placebo-controlled Study

Key Findings:  The β-caryophyllene group showed significant improvement in nausea and epigastric pain, as well as a decrease in the serum IL-1β levels. β-caryophyllene improves dyspepsia symptoms and can be considered a useful supplementary treatment for gastrointestinal disease.

Type of Study:  Double Blind Clinical Trial

Study Sample Size:  66

Study Result:  Positive

Research Location(s):  South Korea

Year of Pub:  2019


Cannabinoids Studied: 

Phytocannabinoid Source:  Not Applicable

Terpenes Studied:  ß-Caryophyllene

Dosage: β-caryophyllene (126 mg/day)

Route of Administration:  Oral (Ingestion)




Citation:  Shim HI, et al. [Inhibitory Effects of β-caryophyllene on Helicobacter pylori Infection: A Randomized Double-blind, Placebo-controlled Study]. Korean J Gastroenterol. 2019; 74:199-204. doi: 10.4166/kjg.2019.74.4.199

Authors:  Shim HI, Song DJ, Shin CM, Yoon H, Park YS, Kim N, Lee DH