Key Findings:  The β-caryophyllene group showed significant improvement in nausea and epigastric pain, as well as a decrease in the serum IL-1β levels. β-caryophyllene improves dyspepsia symptoms and can be considered a useful supplementary treatment for gastrointestinal disease.
Type of Study:  Double Blind Clinical Trial
Study Sample Size:  66
Study Result:  Positive
Research Location(s):  South Korea
Year of Pub:  2019
Cannabinoids Studied: 
Phytocannabinoid Source:  Not Applicable
Terpenes Studied:  ß-Caryophyllene
Dosage: β-caryophyllene (126 mg/day)
Route of Administration:  Oral (Ingestion)
Citation:  Shim HI, et al. [Inhibitory Effects of β-caryophyllene on Helicobacter pylori Infection: A Randomized Double-blind, Placebo-controlled Study]. Korean J Gastroenterol. 2019; 74:199-204. doi: 10.4166/kjg.2019.74.4.199
Authors:  Shim HI, Song DJ, Shin CM, Yoon H, Park YS, Kim N, Lee DH