PRIMARY STUDY
Pharmacological characterization of the cannabinoid receptor 2 agonist, β-caryophyllene on seizure models in mice.
Key Findings: The results suggest that the CB2 receptor agonists might be clinically useful as an adjunct treatment against seizure spread and status epilepticus and concomitant oxidative stress, neurotoxicity and cognitive impairments.
Type of Study: Animal Study
Study Result: Positive
Research Location(s): Brazil, Bulgaria
Year of Pub: 2018
Cannabinoids Studied:
Phytocannabinoid Source: Not Applicable
Terpenes Studied: ß-Caryophyllene
Receptors Studied: CB2
Citation: Tchekalarova J, et al. Pharmacological characterization of the cannabinoid receptor 2 agonist, β-caryophyllene on seizure models in mice. Seizure. 2018; 57:22-26. doi: 10.1016/j.seizure.2018.03.009
Authors: Tchekalarova J, da Conceição Machado K, Gomes Júnior AL, de Carvalho Melo Cavalcante AA, Momchilova A, Tzoneva R
