PRIMARY STUDY
Induction of programmed cell death in Trypanosoma cruzi by Lippia alba essential oils and their major and synergistic terpenes (citral, limonene and caryophyllene oxide).
Key Findings: Citral, caryophyllene oxide, and limonene showed a possible induction of an apoptotic-like phenotype. The best selective anti-T. cruzi activity was achieved by limonene, the effects of which were also synergic with citral, caryophyllene oxide and benznidazole.
Type of Study: Laboratory Study
Study Result: Positive
Research Location(s): Colombia
Year of Pub: 2018
Cannabinoids Studied:
Phytocannabinoid Source: Not Applicable
Terpenes Studied: ß-Caryophyllene
Route of Administration: In vitro
Citation: Moreno ÉM, et al. Induction of programmed cell death in Trypanosoma cruzi by Lippia alba essential oils and their major and synergistic terpenes (citral, limonene and caryophyllene oxide). BMC Complement Altern Med. 2018; 18:225. doi: 10.1186/s12906-018-2293-7
Authors: Moreno ÉM, Leal SM, Stashenko EE, García LT
