PRIMARY STUDY
Moroccan Cannabis sativa essential oil attenuates peripheral neuropathic pain induced by chronic sciatic nerve constriction injury in mice
Key Findings: This study shows that Moroccan Cannabis sativa essential oil—rich in (E)-caryophyllene and α-humulene—significantly reduces neuropathic pain and improves functional recovery in a mouse sciatic nerve injury model, highlighting its terpenoid-driven therapeutic potential.
Type of Study: Animal Study
Study Result: Positive
Research Location(s): Morocco
Year of Pub: 2025
Cannabinoids Studied: Cannabinoid (unspecified)
Phytocannabinoid Source: Not Applicable
Terpenes Studied: ß-Caryophyllene, Humulene
Citation: Kabdy H, Abdelmounaim B, Aitbaba A, Hajar A, Yasmine J, Oufquir S, Agouram F, Laaradraoui J, Aboufatima R, Belbachir A, Garzoli S, Chait A. Moroccan Cannabis sativa essential oil attenuates peripheral neuropathic pain induced by chronic sciatic nerve constriction injury in mice. J Ethnopharmacol. 2025 Mar 13;343:119486. doi: 10.1016/j.jep.2025.119486. Epub 2025 Feb 11. PMID: 39947371.
