PRIMARY STUDY
Select terpenes from Cannabis sativa are antinociceptive in mouse models of post-operative pain and fibromyalgia via adenosine A2a receptors
Key Findings: In this mouse model of post-operative and fibromyalgia pain, geraniol, linalool, β-caryophyllene, and α-humulene provided anti-nociceptive effects.
Type of Study: Animal Study
Study Result: Positive
Research Location(s): United States
Year of Pub: 2025
Cannabinoids Studied: Cannabinoid (unspecified)
Phytocannabinoid Source: Not Applicable
Terpenes Studied: ß-Caryophyllene, Geraniol, Humulene, Linalool
Route of Administration: Injection
Citation: Seekins CA, Welborn AM, Schwarz AM, Streicher JM. Select terpenes from Cannabis sativa are antinociceptive in mouse models of post-operative pain and fibromyalgia via adenosine A2a receptors. Pharmacol Rep. 2025 Feb;77(1):172-181. doi: 10.1007/s43440-024-00687-1. Epub 2024 Dec 12. PMID: 39663308; PMCID: PMC11974608.
