PRIMARY STUDY

Exploring β-caryophyllene: a non-psychotropic cannabinoid's potential in mitigating cognitive impairment induced by sleep deprivation

Key Findings:  This review finds evidence for β-caryophyllene's ability to mitigate key contributors to sleep loss-induced cognitive impairment, such as inflammation, oxidative stress, neuronal death, and reduced neuroplasticity, by modulating various signaling pathways.

Type of Study:  Meta-analysis

Study Result:  Positive

Research Location(s):  Malaysia

Year of Pub:  2025


Cannabinoids Studied:  Cannabinoid (unspecified), Endocannabinoid (unspecified)

Phytocannabinoid Source:  Not Applicable

Terpenes Studied:  ß-Caryophyllene




Citation:  Lim CR, Ogawa S, Kumari Y. Exploring β-caryophyllene: a non-psychotropic cannabinoid's potential in mitigating cognitive impairment induced by sleep deprivation. Arch Pharm Res. 2025 Jan;48(1):1-42. doi: 10.1007/s12272-024-01523-z. Epub 2024 Dec 9. PMID: 39653971.