Cannabinol (CBN) Cannabinoid Research

Cannabinol (CBN) Research Dashboard


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CannaKeys has 99 studies associated with Cannabinol (CBN).

Here is a small sampling of Cannabinol (CBN) studies by title:

Components of the Cannabinol (CBN) Research Dashboard

  • Top medical conditions associated with Cannabinol (CBN)
  • Proven effects in clinical trials for Cannabinol (CBN)
  • Receptors associated with Cannabinol (CBN)
  • Individual study details for Cannabinol (CBN)

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Overview - Cannabinol (CBN)

Description of Cannabinol (CBN)

Cannabinol (CBN) was discovered in 1896 (by Wood, Spivey, and Easterfield) and its chemical structure was reported in 1940 by Roger Adams.

By 2016 there were 13 members in the CBN group.

Most CBN found in cannabis plant material is due to chemical changes that naturally occur during the drying process. As THC begins to degrade over time, some of its chemical composition transforms into CBN. 

Other Names:


Cannabinolum, Cannabinolo, and other supplier-based synonyms.

IUPAC Name: 6,6,9-trimethyl-3-pentylbenzo[c]chromen-1-ol

Molecular Formula: C21H26O2


Cannabinol (CBN) Properties and Effects

CBN may:

  • Induce psychoactive effects (S. Loewe 1945)

  • Modulate significant anti epileptic effects (J. Davis et al., 1949)

  • Generate analgesia

  • Anti-bacterial against MRSA

  • Anti-inflammatory

  • Appetite stimulant

  • Promotes sedation even at low concentrations

Cannabinol (CBN) Receptor Binding

Endocannabinoid system (ECS) and CBN: 

Ki legend:

  • Full/strong agonist Ki ~1-9nM

  • Moderate agonist Ki ~10-99nM

  • Weak agonist Ki ~100-999nM

  • Very weak agonist Ki ~1,000-up nM

(The reader is reminded that a smaller Ki is associated with the strongest effects.)

Disclaimers: Information on this site is provided for informational purposes only and is not meant to substitute for the advice provided by your own physician or other medical professional. You should not use the information contained herein for diagnosing a health problem or disease. If using a product, you should read carefully all product packaging. If you have or suspect that you have a medical problem, promptly contact your health care provider.

Information on this site is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your physician, nutritionally oriented health care practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications.