Cannabinol (CBN) Cannabinoid Research

Cannabinol (CBN) Research Dashboard


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CannaKeys has 81 studies associated with Cannabinol (CBN).

Here is a small sampling of Cannabinol (CBN) studies by title:

Components of the Cannabinol (CBN) Research Dashboard

  • Top medical conditions associated with Cannabinol (CBN)
  • Proven effects in clinical trials for Cannabinol (CBN)
  • Receptors associated with Cannabinol (CBN)
  • Individual study details for Cannabinol (CBN)

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Overview - Cannabinol (CBN)

Description of Cannabinol (CBN)

The plant-based (phytocannabinoid) Cannabinol was discovered in 1896 (by Wood, Spivey, and Easterfield) and its chemical structure was determined in 1940 (by Roger Adams). By 2016 there were 13 members in the CBN group. Most CBN found in cannabis plant material is due to chemical changes that naturally occur during the drying process. As THC begins to degrade over time, some of its chemical composition transforms into CBN. Research seems to indicated that CBN promotes sedation even at low concentrations. CBN is not a mind-altering cannabinoid or at best is a very mild psychoactive compound.

Other Names:

Cannabinolum, Cannabinolo, and others.

IUPAC Name: 6,6,9-trimethyl-3-pentylbenzo[c]chromen-1-ol

Molecular Formula: C21H26O2


Cannabinol (CBN) Properties and Effects

• Analgesia
• Anti-bacterial against MRSA
• Anti-inflammatory
• Appetite stimulant
• Epidermolysis bullosa

Cannabinol (CBN) Receptor Binding

Endocannabinoid system (ECS)
• Agonist at CB1 (~ten times lower than delta-9-THC; Chiara Maioli et al. 2022)
• Agonist at CB2 (mixed results suggesting equal to ~3 times lower than delta-9-THC; Chiara Maioli et al. 2022)

Disclaimers: Information on this site is provided for informational purposes only and is not meant to substitute for the advice provided by your own physician or other medical professional. You should not use the information contained herein for diagnosing a health problem or disease. If using a product, you should read carefully all product packaging. If you have or suspect that you have a medical problem, promptly contact your health care provider.

Information on this site is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your physician, nutritionally oriented health care practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications.