Cannabinol (CBN) Research Dashboard
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Overview - Cannabinol (CBN)
Description of Cannabinol (CBN)
Cannabinol (CBN) was discovered in 1896 (by Wood, Spivey, and Easterfield), and its chemical structure was reported in 1940 by Roger Adams.
Non-enzymatic oxidative degradation of THCA associated with exposure to oxygen or UV radiation converts THCA into cannabinolic acid (CBNA), CBN's acidic form and precursor. As cannabis ages, the carboxyl group is removed, leaving CBN in its place. Both CBNA and CBN are found naturally only in very low concentrations in the plant. According to a toxicometabolomic study, CBN concentration in cannabis leaves ranges between 0.1 and 1.6% (w/w of dry weight) (I. Chousidis et al., 2020)
By 2016 there were 13 members in the CBN group.
CBN Psychoactivity: A quick look at the receptor binding window shows that CBN binds to the same CB1 receptor sites (abundantly present in the brain) as THC but with a weaker affinity meaning that it can still induce changes in cognition and mood but only at about one-tenth of the strength of THC.
Other Names:
CannabinolCannabinolum, Cannabinolo, and other supplier-based synonyms.
IUPAC Name: 6,6,9-trimethyl-3-pentylbenzo[c]chromen-1-ol
Molecular Formula: C21H26O2
Source–PubChem
Cannabinol (CBN) Properties and Effects
Only Members can view Properties and Effects information. See DEMO page.
Cannabinol (CBN) Receptor Binding
Only Members can view Receptor Binding information. See DEMO page.
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