Anandamide (AEA) Research Dashboard
Double-blind human trials
Clinical human trials
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As a subscriber, you will be able to access dashboard insights including chemotype overviews and dosing summaries for medical conditions and organ system and receptor breakdowns for cannabinoid and terpene searches. Study lists present important guidance including dosing and chemotype information with the ability to drill down to the published material. And all outputs are fully filterable, to help find just the information you need. Stay up-to-date with the science of cannabis and the endocannabinoid system with CannaKeys.
CannaKeys has 246 studies associated with Anandamide (AEA).
Here is a small sampling of Anandamide (AEA) studies by title:
- Cannabinoids and Hormone Receptor-Positive Breast Cancer Treatment
- Anandamide Metabolites Protect against Seizures through the TRP Channel Water Witch in Drosophila melanogaster
- Endocannabinoid System and Cannabinoid 1 Receptors in Patients With Pharmacoresistant Temporal Lobe Epilepsy and Comorbid Mood Disorders
- Cannabidiol increases the nociceptive threshold in a preclinical model of Parkinson's disease
- A new role for anandamide: defective link between the systemic and skin endocannabinoid systems in hypertrophic human wound healing
Components of the Anandamide (AEA) Research Dashboard
- Top medical conditions associated with Anandamide (AEA)
- Proven effects in clinical trials for Anandamide (AEA)
- Receptors associated with Anandamide (AEA)
- Individual study details for Anandamide (AEA)
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Members can filter by the following criteria:
- Study Type
- Organ Systems
- Study Result
- Year of Publication
Overview - Anandamide (AEA)
Description of Anandamide (AEA)
Anandamide was the first endogenous (naturally occurring inside the human body) cannabinoid to be discovered by Raphael Mechoulam in 1995. Mechoulam and his team named the compound combining the Sanskrit word for bliss, "ananda," and the word "amide" describing an organic chemical compound to arrive at the name anandamide. The naturally occurring enzyme fatty acid amide hydrolase (FAAH) breaks down AEA.
Anandamide (N-arachidonyl ethanolamide)
Anandamide (AEA) Properties and Effects
Anti-inflammatory via PPAR-Gamma, TRPV1 induced vasodilation
Anandamide (AEA) Receptor Binding
Weak affinity for CB1 with a mean Ki 239.2nM. Weak affinity for CB2 with a mean Ki 439.5nM. Binds with TRPV1. Binds with PPARy with an EC50 of 8 μM.
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Information on this site is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your physician, nutritionally oriented health care practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications.