5F-x Synthetic Cannabinoids Cannabinoid Research

5F-x Synthetic Cannabinoids Research Dashboard


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As a subscriber, you will be able to access dashboard insights including chemotype overviews and dosing summaries for medical conditions and organ system and receptor breakdowns for cannabinoid and terpene searches. Study lists present important guidance including dosing and chemotype information with the ability to drill down to the published material. And all outputs are fully filterable, to help find just the information you need. Stay up-to-date with the science of cannabis and the endocannabinoid system with CannaKeys.

CannaKeys has 22 studies associated with 5F-x Synthetic Cannabinoids.

Here is a small sampling of 5F-x Synthetic Cannabinoids studies by title:

Components of the 5F-x Synthetic Cannabinoids Research Dashboard

  • Top medical conditions associated with 5F-x Synthetic Cannabinoids
  • Proven effects in clinical trials for 5F-x Synthetic Cannabinoids
  • Receptors associated with 5F-x Synthetic Cannabinoids
  • Individual study details for 5F-x Synthetic Cannabinoids

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Overview - 5F-x Synthetic Cannabinoids

Description of 5F-x Synthetic Cannabinoids

5F-MDMB-PICA emerged as a novel "herbal" ingredient in drugs of the European recreational market in 2016 (under the names of e.g., "K2", "Spice") and was the most commonly available synthetic cannabinoid in the USA between 2019 and 2020. It is one of the more potent members and is associated with serious adverse health, behavioral effects and deaths.

Here we focus on 5F-MDMB-PICA.

Other potentially clinically relevant members may include 5F-AMBICA, 5F-AMB (full agonist at CB1), 5F-ADB, 5F-MDMB-PINACA.

5F-x class of synthetic cannabinoids are identified by their 5-flouropentyl chain.

Other Names:

5F-x Family of Synthetic Cannabinoids


IUPAC Name: methyl (2S)-2-[[1-(5-fluoropentyl)indole-3-carbonyl]amino]-3,3-dimethylbutanoate

Molecular Formula: C21H29FN2O3


5F-x Synthetic Cannabinoids Properties and Effects

Only Members can view Properties and Effects information. See DEMO page.

5F-x Synthetic Cannabinoids Receptor Binding

Only Members can view Receptor Binding information. See DEMO page.

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Information on this site is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your physician, nutritionally oriented health care practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications.