5F-x Synthetic Cannabinoids Research Dashboard
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As a subscriber, you will be able to access dashboard insights including chemotype overviews and dosing summaries for medical conditions and organ system and receptor breakdowns for cannabinoid and terpene searches. Study lists present important guidance including dosing and chemotype information with the ability to drill down to the published material. And all outputs are fully filterable, to help find just the information you need. Stay up-to-date with the science of cannabis and the endocannabinoid system with CannaKeys.
CannaKeys has 19 studies associated with 5F-x Synthetic Cannabinoids.
Here is a small sampling of 5F-x Synthetic Cannabinoids studies by title:
- Methyl (S)-2-(1-7 (5-fluoropentyl)-1H-indole-3-carboxamido)-3,3-dimethylbutanoate (5F-MDMB-PICA) intoxication in a child with identification of two new metabolites (ultra-high-performance liquid chromatography-tandem mass spectrometry)
- 'Flying high?'-Jump from a height in a 'Spice' high?: A case report on the synthetic cannabinoid 5F-MDMB-P7AICA
- Structure-activity relationships for 5F-MDMB-PICA and its 5F-pentylindole analogs to induce cannabinoid-like effects in mice
- Fatal intoxication with new synthetic cannabinoids 5F-MDMB-PICA and 4F-MDMB-BINACA—parent compounds and metabolite identification in blood, urine and cerebrospinal fluid
- In vitro and in vivo pharmacology of nine novel synthetic cannabinoid receptor agonists
Components of the 5F-x Synthetic Cannabinoids Research Dashboard
- Top medical conditions associated with 5F-x Synthetic Cannabinoids
- Proven effects in clinical trials for 5F-x Synthetic Cannabinoids
- Receptors associated with 5F-x Synthetic Cannabinoids
- Individual study details for 5F-x Synthetic Cannabinoids
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Overview - 5F-x Synthetic Cannabinoids
Description of 5F-x Synthetic Cannabinoids
5F-MDMB-PICA emerged as a novel "herbal" ingredient in drugs of the European recreational market in 2016 (under the names of e.g., "K2", "Spice") and was the most commonly available synthetic cannabinoid in the USA between 2019 and 2020. It is one of the more potent members and is associated with serious adverse health, behavioral effects and deaths.
Here we focus on 5F-MDMB-PICA.
Other potentially clinically relevant members may include 5F-AMBICA, 5F-AMB (full agonist at CB1), 5F-ADB, 5F-MDMB-PINACA.
5F-x class of synthetic cannabinoids are identified by their 5-flouropentyl chain.
Other Names:
5F-x Family of Synthetic Cannabinoids5F-MDMB-PICA
IUPAC Name: methyl (2S)-2-[[1-(5-fluoropentyl)indole-3-carbonyl]amino]-3,3-dimethylbutanoate
Molecular Formula: C21H29FN2O3
Source–PubChem
5F-x Synthetic Cannabinoids Properties and Effects
Only Members can view Properties and Effects information. See DEMO page.
5F-x Synthetic Cannabinoids Receptor Binding
Only Members can view Receptor Binding information. See DEMO page.
Disclaimer
Information on this site is provided for informational purposes only and is not meant to substitute for the advice provided by your own licensed physician or other medical professional. You
should not use the information contained herein for diagnosing or treating a health problem or disease. If using a product, you should read carefully all product packaging. If you have or suspect that you have a
medical problem, promptly contact your health care provider.
Information on this site is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your physician, nutritionally oriented health care practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications.
