Key Findings:  We have provided the first evidence on the up-regulation of CB2 receptors in glial elements in postmortem tissues of PD patients, which has been confirmed in an inflammatory model of this disease. In addition, we have provided evidence on the benefits derived from their activation in relation with the activation of microglial cells, the infiltration of macrophages and also certain capability of these cells to generate proinflammatory factors.
Type of Study:  Animal Study
Study Result:  Positive
Cannabinoids Studied:  HU-x Synthetic Cannabinoids
Phytocannabinoid Source:  Not Applicable