Key Findings:  This review discusses the evolving science and understanding of cannabis and the endocannabinoid system as well as changing social, political, and legislative stances on the use and cultivation of cannabis. There is evidence for both positive and negative use cases for cannabis and the author calls for far more research on the subject.
Type of Study:  Meta-analysis
Study Sample Size:  6
Study Result:  Inconclusive
Study Location(s):  United States
Year of Pub:  2022
Cannabinoids Studied:  Cannabichromene (CBC), Cannabidiol (CBD), Cannabigerol (CBG), Tetrahydrocannabinol (THC), Cannabinol (CBN), Anandamide (AEA), Fatty Acid Amide Hydrolase (FAAH), 2-Arachidonoyl Glycerol (2-AG), Synthetic Cannabinoid (unspecified), Endocannabinoid (unspecified), Pharma THC, Tetrahydrocannabivarin (THCV), Delta-8-THC
Phytocannabinoid Source:  Unspecified
Receptors Studied:  CB1, CB2, GPCR 55, TRPV1, CB1 antagonist
Ligands Studied:  Serotonin
Route of Administration:  Endogenous, Inhalation, Oral (Ingestion), Sublingual/Oromucosal