RELATED STUDY

Cannabinoids for treating inflammatory bowel diseases: where are we and where do we go?

Key Findings:  Most evidence points toward an involvement of CB1 and also CB2 receptors, especially with regard to immune cell recruitment. Further research in this direction, preferably on human IBD material, such as explants, cultured biopsies, etc. is highly warranted.

Type of Study:  Meta-analysis

Study Result:  Positive

Study Location(s):  Austria, Germany

Year of Pub:  2017


Cannabinoids Studied:  Anandamide (AEA), Fatty Acid Amide Hydrolase (FAAH), 2-Arachidonoyl Glycerol (2-AG), Monoacylglycerol Lipase (MAGL), Cannabinoid (unspecified), Synthetic Cannabinoid (unspecified), Endocannabinoid (unspecified), Pharma THC, Pharma THC:CBD

Phytocannabinoid Source:  Not Applicable

Chemotype:  Chemotype I, Chemotype II

Receptors Studied:  CB1, CB2, GPCR 55, TRPV1, PPAR - Alpha, GPCR, TRPs, PPARs

Ligands Studied:  Anti-inflammatory cytokines, Pro-inflammatory cytokines