PRIMARY STUDY
Cannabidiol and palmitoylethanolamide are anti-inflammatory in the acutely inflamed human colon.
Key Findings: Palmitoylethanolamide (PEA) and CBD are anti-inflammatory in the human colon. This effect is not seen in cultured epithelial cells. Appropriately sized clinical trials should assess their efficacy.
Type of Study: Laboratory Study
Study Result: Positive
Study Location(s): United Kingdom
Year of Pub: 2017
Cannabinoids Studied: Cannabidiol (CBD), AM-x Synthetic Cannabinoids, Synthetic Cannabinoid (unspecified), Palmitoylethanolamide (PEA)
Phytocannabinoid Source: Not Applicable
Chemotype: Chemotype III
Receptors Studied: CB1, CB2, GPCR 55, TRPV1, PPAR - Gamma
Ligands Studied: Anti-inflammatory cytokines, Pro-inflammatory cytokines
