Cannabis exposure during adolescence: A uniquely sensitive period for neurobiological effects

Key Findings:  This review covers the role of the endocannabinoid system (ECS) in the adolescent brain, and how exposure to THC and modulation of the ECS, specifically CB1 receptors, in the developing brain can alter neurobiological processes across the lifespan and increases the potential to develop conditions like psychosis, schizophrenia, and addiction among others.

Type of Study:  Meta-analysis

Study Result:  Negative

Study Location(s):  United Kingdom, United States

Year of Pub:  2021

Cannabinoids Studied:  Tetrahydrocannabinol (THC), Cannabinoid (unspecified), Endocannabinoid (unspecified)

Phytocannabinoid Source:  Not Applicable

Chemotype:  Chemotype I

Receptors Studied:  CB1

Ligands Studied:  Dopamine