Key Findings:  This review covers the role of the endocannabinoid system (ECS) in the adolescent brain, and how exposure to THC and modulation of the ECS, specifically CB1 receptors, in the developing brain can alter neurobiological processes across the lifespan and increases the potential to develop conditions like psychosis, schizophrenia, and addiction among others.
Type of Study:  Meta-analysis
Study Result:  Negative
Study Location(s):  United Kingdom, United States
Year of Pub:  2021
Cannabinoids Studied:  Tetrahydrocannabinol (THC), Cannabinoid (unspecified), Endocannabinoid (unspecified)
Phytocannabinoid Source:  Not Applicable
Chemotype:  Chemotype I
Receptors Studied:  CB1
Ligands Studied:  Dopamine