RELATED STUDY
In vitro percutaneous absorption studies of cannabidiol using human skin: Exploring the effect of drug concentration, chemical enhancers, and essential oils
Key Findings: This study aimed to evaluate the absorption of cannabidiol (CBD) in different mediums into human skin cells. There was no difference in the absorption based on the concentration of CBD, 5% vs 10%. Oleic acid enhanced absorption, while essential oils had less absorption when compared to the control group. This information may provide practical application to improve the topical use of CBD in treating skin conditions.
Type of Study: Laboratory Study
Study Result: Positive
Study Location(s): United States
Year of Pub: 2022
Cannabinoids Studied: Cannabichromene (CBC), Cannabidiol (CBD), Cannabigerol (CBG), Tetrahydrocannabinol (THC), CP-x Synthetic Cannabinoids, AM-x Synthetic Cannabinoids, JWH-x Synthetic Cannabinoids, HU-x Synthetic Cannabinoids, WIN-x Synthetic Cannabinoids, Anandamide (AEA), 2-Arachidonoyl Glycerol (2-AG), Virodhamine (O-AEA), Pharma CBD, Tetrahydrocannabivarin (THCV), Delta-8-THC, Cannabidivarin (CBDV), Palmitoylethanolamide (PEA)
Phytocannabinoid Source: Cannabis Flower derived
Chemotype: Chemotype III
Receptors Studied: CB1, CB2, GPCR 18, GPCR 55, TRPA1, TRPV1, TRPV2, TRPV4, TRPM8, GPCR, TRPs
DOSING DETAILS 
Study Dosing Objective: Effective Dose
Established Protocol: Effective dose
Route of Administration: Topical
Cannabinoid Ratio: (CBD) 0 
Dosing Regimen: CBD (242.41 or 232.79 µg/cm2)
Link to study
