Key Findings:  This case study reviews a 9-year-old patient with debilitating symptoms related to autism spectrum disorder (ASD) who was treated with a combination of high-dose cannabidiol (CBD) and low-dose tetrahydrocannabinol (THC) oil. Results included a reduction in negative behaviors and an improved quality of life for both the patient and the caregivers.
Type of Study:  Meta-analysis
Study Sample Size:  1
Study Result:  Positive
Study Location(s):  Canada
Year of Pub:  2022
Cannabinoids Studied:  Cannabidiol (CBD), Tetrahydrocannabinol (THC), Anandamide (AEA), Fatty Acid Amide Hydrolase (FAAH), 2-Arachidonoyl Glycerol (2-AG), Monoacylglycerol Lipase (MAGL)
Phytocannabinoid Source:  Unspecified
Chemotype:  Chemotype III
Receptors Studied:  CB1, CB2
Sub-Ratio: THC:CBD 1:20
Dosage: CBD 20 mg/mL THC <1 mg/mL Dose: 0.1ml twice daily, increased every three to four days to 0.5ml twice daily
Route of Administration:  Oral (Ingestion)