PRIMARY STUDY

Beta-caryophyllene prevents the defects in trabecular bone caused by Vitamin D deficiency through pathways instated by increased expression of klotho

Key Findings:  This mouse study found that diets enhanced with β-caryophyllene (BCP) led to elevated levels of klotho which in mice improves bone volume and density. In mice klotho also regulates CB1 and fibroblast growth factors.