Plasma anandamide concentrations are lower in children with autism spectrum disorder.

Key Findings:  Children with lower anandamide concentrations were more likely to have ASD. These findings are the first empirical human data to translate preclinical rodent findings to confirm a link between plasma anandamide concentrations in children with ASD. Although preliminary, these data suggest that impaired anandamide signaling may be involved in the pathophysiology of ASD.

Type of Study:  Meta-analysis

Study Result:  Positive

Study Location(s):  United States

Year of Pub:  2018

Cannabinoids Studied:  Anandamide (AEA)

Phytocannabinoid Source:  Not Applicable