PRIMARY STUDY

β-Caryophyllene, a CB2-Receptor-Selective Phytocannabinoid, Suppresses Mechanical Allodynia in a Mouse Model of Antiretroviral-Induced Neuropathic Pain

Key Findings:  β-Caryophyllene prevents NRTI-induced mechanical allodynia, possibly via reducing the inflammatory response, and attenuates mechanical allodynia through CB2 receptor activation.

Type of Study:  Animal Study

Study Result:  Positive

Study Location(s):  Kuwait

Year of Pub:  2019


Cannabinoids Studied:  AM-x Synthetic Cannabinoids

Phytocannabinoid Source:  Not Applicable

Terpenes Studied:  ß-Caryophyllene

Receptors Studied:  CB2

Ligands Studied:  Anti-inflammatory cytokines