RELATED STUDY
Biomarkers of Recent Cannabis Use in Blood, Oral Fluid and Breath
Key Findings: This study measured levels of 10 different cannabinoids in the blood, saliva, and breath of frequent versus occasional cannabis users. They were randomized to receive cigarettes containing either a placebo or THC (5.9% or 13.4%). Saliva levels of THC were most sensitive to recent cannabis use but did not lend information on the level or duration of impairment. This work may help develop better biomarker tests for cannabis use and levels of impairment.
Type of Study: Double Blind Clinical Trial
Study Sample Size: 191
Study Result: Inconclusive
Research Location(s): United States
Year of Pub: 2021
Cannabinoids Studied: Cannabidiol (CBD), Cannabigerol (CBG), Tetrahydrocannabinol (THC), Cannabinol (CBN), Tetrahydrocannabinolic Acid (THC-a), Cannabinoid (unspecified), Tetrahydrocannabivarin (THCV)
Phytocannabinoid Source: Cannabis Flower derived
Route of Administration: Inhalation
Citation: Hubbard JA, et al. Biomarkers of Recent Cannabis Use in Blood, Oral Fluid and Breath. J Anal Toxicol. 2021; 45:820-828. doi: 10.1093/jat/bkab080
Authors: Hubbard JA, Hoffman MA, Ellis SE, Sobolesky PM, Smith BE, Suhandynata RT, Sones EG, Sanford SK, Umlauf A, Huestis MA, Grelotti DJ, Grant I, Marcotte TD, Fitzgerald RL
