Key Findings:  Cannabidiol selectively reduces croton oil-induced hypermotility in mice in vivo and this effect involves cannabinoid CB1 receptors and FAAH. In view of its low toxicity in humans, cannabidiol may represent a good candidate to normalize motility in patients with inflammatory bowel disease.
Type of Study:  Animal Study
Study Result:  Positive
Study Location(s):  Italy
Year of Pub:  2008
Cannabinoids Studied:  Cannabidiol (CBD), JWH-x Synthetic Cannabinoids, SR-x Synthetic Cannabinoids, Fatty Acid Amide Hydrolase (FAAH)
Chemotype:  Chemotype III
Receptors Studied:  CB1, CB2
Sub-Ratio: 0:1 (THC:CBD)
Dosage: CBD (1–10 mg kg−1) i.p.
Route of Administration:  Injection