RELATED STUDY

Treatment of Ovarian Hyperstimulation Syndrome in a Mouse Model by Cannabidiol, an Angiogenesis Pathway Inhibitor

Key Findings:  This study aimed to investigate the role of the endocannabinoid system and cannabidiol (CBD) on the mechanism of action in ovarian hyperstimulation syndrome (OHSS). The CBD group had a significant decrease in body and ovary weight, decreased vascular permeability, follicular count, and VEGF expression, suggesting CBD's antiangiogenic activity could be effective in counteracting the development of OHSS.

Type of Study:  Animal Study

Study Sample Size:  32

Study Result:  Positive

Study Location(s):  Iran

Year of Pub:  2022


Cannabinoids Studied:  Cannabidiol (CBD)

Phytocannabinoid Source:  Unspecified

Chemotype:  Chemotype III

Ligands Studied:  Anti-inflammatory cytokines, Estrogen, Serotonin, Pro-inflammatory cytokines

Dosage: CBD (30 mg/kg)

Route of Administration:  Oral (Ingestion)



Link to study