PRIMARY STUDY

Up-regulation of anandamide levels as an endogenous mechanism and a pharmacological strategy to limit colon inflammation

Key Findings:  This study of colon inflammation found that anandamide (AEA) levels are elevated in human ulcerative colitis samples, as well as animal inflammatory bowel disease (IBD) models. By increasing AEA levels and inhibiting its reuptake the anti-inflammation effects of the endocannabinoid system may lead be novel therapeutic agents for the treatment of these gastrointestinal conditions.