PRIMARY STUDY

Neuroprotective Effect of β-Caryophyllene on Cerebral Ischemia-Reperfusion Injury via Regulation of Necroptotic Neuronal Death and Inflammation: In Vivo and in Vitro

Key Findings:  BCP alleviates ischemic brain damage potentially by inhibiting necroptotic neuronal death and inflammatory response. This study suggests a novel application for BCP as a neuroprotective agent.

Type of Study:  Animal Study

Study Result:  Positive

Study Location(s):  China, United States

Year of Pub:  2017


Cannabinoids Studied: 

Phytocannabinoid Source:  Not Applicable

Terpenes Studied:  ß-Caryophyllene

Receptors Studied:  CB2

Ligands Studied:  Anti-inflammatory cytokines, Pro-inflammatory cytokines

Dosage: BCP (8, 24, 72 mg/kg, ip.)

Route of Administration:  Injection



Link to study