Key Findings:  This extensive review covers the endocannabinoid system, specifically cannabinoid receptors, and the effect of exogenous cannabinoids on neuroinflammatory diseases such as Alzheimer's, Huntington's, Parkinson's, and Multiple Sclerosis.
Type of Study:  Meta-analysis
Study Result:  Positive
Study Location(s):  Ireland, Romania
Year of Pub:  2022
Cannabinoids Studied:  Cannabidiol (CBD), Tetrahydrocannabinol (THC), AM-x Synthetic Cannabinoids, JWH-x Synthetic Cannabinoids, HU-x Synthetic Cannabinoids, WIN-x Synthetic Cannabinoids, Anandamide (AEA), Fatty Acid Amide Hydrolase (FAAH), 2-Arachidonoyl Glycerol (2-AG), Monoacylglycerol Lipase (MAGL), Endocannabinoid (unspecified), Pharma THC
Phytocannabinoid Source:  Not Applicable
Receptors Studied:  CB1, CB2, TRPV1, PPAR - Gamma, GPCR
Ligands Studied:  Dopamine, Epinephrine, Glutamate, Norepinephrine, Serotonin, Pro-inflammatory cytokines