PRIMARY STUDY

Engineered Lactobacillus paracasei Producing Palmitoylethanolamide (PEA) Prevents Colitis in Mice

Key Findings:  Administration of palmitoylethanolamide (PEA) to mice in this model of ulcerative colitis (UC) found a significant reduction in inflammatory markers and cellular damage suggesting potential therapeutic use of PEA in the treatment of inflammatory bowel and intestinal disease, as in UC.