PRIMARY STUDY

Effects of cannabinoids Δ(9)-tetrahydrocannabinol, Δ(9)-tetrahydrocannabinolic acid and cannabidiol in MPP+ affected murine mesencephalic cultures.

Key Findings:  MPP(+) is an established model compound in the research of parkinsonism. Our data show that cannabinoids THC and THCA protect dopaminergic neurons against MPP(+) induced cell death.

Type of Study:  Laboratory Study

Study Result:  Positive


Cannabinoids Studied:  Cannabidiol (CBD), Tetrahydrocannabinol (THC), Tetrahydrocannabinolic Acid (THC-a)

Phytocannabinoid Source:  Not Applicable

Form of Administration:  Not Applicable

Ligands Studied:  Dopamine


Study Location(s):  Austria

Year of Pub:  2012


Link to study