Cannabidiol as an Emergent Therapeutic Strategy for Lessening the Impact of Inflammation on Oxidative Stress.

Key Findings:  This review discusses recent studies suggesting that cannabidiol may have utility in treating a number of human diseases and disorders now known to involve activation of the immune system and associated oxidative stress, as a contributor to their etiology and progression. These include rheumatoid arthritis, types I and II diabetes, atherosclerosis, Alzheimer’s disease, hypertension, the metabolic syndrome, ischemia-reperfusion injury, depression, and neuropathic pain.

Type of Study:  Meta-analysis

Study Result:  Positive

Cannabinoids Studied:  Cannabidiol (CBD), Fatty Acid Amide Hydrolase (FAAH)

Phytocannabinoid Source:  Not Applicable

Chemotype:  Chemotype III

Form of Administration:  Not Applicable

Receptors Studied:  CB1, CB2, GPCR 55, PPAR - Gamma, PPARs

Ligands Studied:  Anti-inflammatory cytokines, Glutamate, Serotonin, Pro-inflammatory cytokines

Study Location(s):  United States

Year of Pub:  2011

Link to study