Melatonin and cannabinoids: mitochondrial-targeted molecules that may reduce inflammaging in neurodegenerative diseases

Key Findings:  Senescence and autophagic processes may play a crucial role in neuro-inflammatory pathologies associated with aging. Melatonin and cannabinoids as well as their associated receptor sites (which are closely related) may exert anti-aging effects with direct relevance to Parkinson's and Alzheimer's diseases for example.

Type of Study:  Meta-analysis

Study Result:  Positive

Cannabinoids Studied:  Cannabinoid (unspecified)

Phytocannabinoid Source:  Unspecified

Form of Administration:  Not Applicable

Ligands Studied:  Anti-inflammatory cytokines, Pro-inflammatory cytokines, Not Applicable

Study Location(s):  Argentina, United States

Year of Pub:  2020

Link to study