PRIMARY STUDY

Cannabidiol for the treatment of psychosis in Parkinson's disease

Key Findings:  In this open-label pilot study 6 outpatients diagnosed with PD and psychotic episodes for at least 3 months received CBD as a flexible dose (starting with an oral dose of 150 mg/day) for 4 weeks in addition to their pharmaceutical regime. Data revealed a significant reduction in psychotic symptoms a decrease in the total scores of the Unified Parkinson's Disease Rating Scale. No adverse effect were observed. The authors posit that CBD may be effective and safe treatment in this particular patient population.