PRIMARY STUDY
Cannabidiol increases the nociceptive threshold in a preclinical model of Parkinson's disease
Key Findings: CBD reduces hyperalgesia and allodynia in an animal model of PD; CB1 and TRPV1 receptor activation may be involved in CBD-induced analgesia; additionally, CBD may induce analgesic effects increasing level of the endogenous cannabinoid anandamide.
Type of Study: Animal Study
Study Result: Positive
Study Location(s): Brazil
Year of Pub: 2020
Cannabinoids Studied: Cannabidiol (CBD), Anandamide (AEA)
Phytocannabinoid Source: Unspecified
Chemotype: Chemotype III
Receptors Studied: CB1, TRPV1
