PRIMARY STUDY

Cannabidiol increases the nociceptive threshold in a preclinical model of Parkinson's disease

Key Findings:  CBD reduces hyperalgesia and allodynia in an animal model of PD; CB1 and TRPV1 receptor activation may be involved in CBD-induced analgesia; additionally, CBD may induce analgesic effects increasing level of the endogenous cannabinoid anandamide.

Type of Study:  Animal Study

Study Result:  Positive


Cannabinoids Studied:  Cannabidiol (CBD), Anandamide (AEA)

Phytocannabinoid Source:  Unspecified

Chemotype:  Chemotype III

Form of Administration:  Not Applicable

Receptors Studied:  CB1, TRPV1


Study Location(s):  Brazil

Year of Pub:  2020


Link to study