PRIMARY STUDY

Acute administration of beta-caryophyllene prevents endocannabinoid system activation during transient common carotid artery occlusion and reperfusion.

Key Findings:  Collectively, the pre-treatment with BCP, likely acting as agonist for CB2 and PPAR-alpha receptors, modulates in a beneficial way the ECS activation and the lipoperoxidation, taken as indicative of oxidative stress. Furthermore, results support the evidence that BCP may be used as a dietary supplement to control the physiological response to the hypoperfusion/reperfusion-induced oxidative stress.

Type of Study:  Animal Study

Study Result:  Positive

Study Location(s):  Italy

Year of Pub:  2018


Cannabinoids Studied: 

Terpenes Studied:  ß-Caryophyllene

Receptors Studied:  CB2, PPAR - Alpha

Dosage: β-caryophyllene (40 mg/per rat in 300 μl of sunflower oil as vehicle) 6 h before surgery

Route of Administration:  Oral (Ingestion)



Link to study