Cannabinoid Receptors and Endocannabinoids: Role in Neuroinflammatory and Neurodegenerative Disorders

Key Findings:  The neuro-modulatory actions at CB1 receptors by endocannabinoids, of which anandamide and 2-arachidonoylglycerol are the two most studied representatives, allows them to counteract the neuro-chemical imbalances arising during Alzheimer’s disease, multiple sclerosis, amyotropic lateral sclerosis, Parkinson’s disease, and Huntington’s chorea.

Type of Study:  Meta-analysis

Study Result:  Positive

Cannabinoids Studied:  Anandamide (AEA), 2-Arachidonoyl Glycerol (2-AG)

Phytocannabinoid Source:  Not Applicable

Form of Administration:  Not Applicable

Receptors Studied:  CB1

Study Location(s):  Italy

Year of Pub:  2010

Link to study