PRIMARY STUDY
Experimental colitis in mice is attenuated by changes in the levels of endocannabinoid metabolites induced by selective inhibition of fatty acid amide hydrolase (FAAH)
Key Findings: Using an FAAH inhibitor (PF-3845) researchers discovered that FAAH-dependent endocannabinoids play a significant role in colitis.
Type of Study: Animal Study
Study Result: Positive
Study Location(s): Germany, Poland, United States
Year of Pub: 2014
Cannabinoids Studied: AM-x Synthetic Cannabinoids, Fatty Acid Amide Hydrolase (FAAH), Synthetic Cannabinoid (unspecified)
Phytocannabinoid Source: Not Applicable
Receptors Studied: CB1, CB2
Ligands Studied: Anti-inflammatory cytokines, Pro-inflammatory cytokines
