PRIMARY STUDY

A Randomized, Double-blind, Placebo-controlled, Parallel-group, Pilot Study of Cannabidiol-rich Botanical Extract in the Symptomatic Treatment of Ulcerative Colitis

Key Findings:  Although there was no remission, the subjective physician's overall assessment of illness severity, as well as patients subjective reports suggest improvements in quality-of-life outcomes in patients taking CBD-rich botanical extract. Adverse events were mostly mild/moderate with many in the CBD-rich botanical extract group potentially attributable to the ∆9-tetrahydrocannabinol content. suggest CBD-rich botanical extract may be beneficial for symptomatic treatment of UC

Type of Study:  Double Blind Clinical Trial

Study Sample Size:  60

Study Result:  Positive

Study Location(s):  United Kingdom

Year of Pub:  2019


Cannabinoids Studied:  Cannabidiol (CBD), Tetrahydrocannabinol (THC), Cannabinoid (unspecified)

Phytocannabinoid Source:  Unspecified

Chemotype:  Chemotype III

Sub-Ratio: 0:1 (THC:CBD)

Dosage: CBD (50 to 250 mg in CBD rich botanical extract with a small percentage of THC)

Route of Administration:  Oral (Ingestion)



Link to study